You can drive to Alaska from anywhere in the United States except Hawaii. Use the mapquest driving directions to find the fastest way. 

The Alaska Highway is the sole main road between Alaska and the rest of the United States. You will ultimately join the Alaska Highway, regardless of where you begin in the United States or Canada.

The Alaska Highway was created during World War II to connect the Lower 48 States to Alaska without having to travel by sea. It first opened to the public in 1948.

British Columbia Highway 97, Yukon Highway 1, and Alaska Route 2 are the three highways that make up the highway.

Although the original road was difficult to drive and was 1,700 miles (2,700 kilometers) long, it has been renovated through time and is now totally paved all the way and is only 1,387 miles long (2,232 km).

Driving to Alaska from the United States

On the navigation mapquest directions, I see there are 4 different routes to Alaska depending on where in the United States you are starting your journey from.

The great majority of Americans will go through North Dakota to enter Canada at the Portal or Fortuna border crossings. Mountain Standard Time residents will enter Canada through the Sweetgrass or Piegan–Carway borders in Montana, while West Coast residents will enter Canada at Sumas near Vancouver.

The only exception is for individuals who live in Maine, where the best way to get to Alaska is to travel down the Trans-Canada Highway, which is 4,500 miles one way. Examine whether you really want to do that rather than flying and renting a car at the other end!